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[Disorders of pulmonary circulation in man].
In the pulmonary circulation the resistance to the flow increases along the pulmonary vascular bed. This increase of the total pulmonary vascular resistance, represents the main factor that prevents the “upstream dilatation” during exercise. During exercise, as blood flow increases and the pressure in the pulmonary circulation decreases, then the pressure gradient between the right ventricle and the pulmonary circulation is reduced and this mechanism in part compensates the increased pulmonary vascular resistance. On the opposite, in the blood flow decrease during exercise, the “upstream dilatation” is the main mechanism to increase the pulmonary blood flow. The pulmonary vascular bed is responsible for the conservation of the pulmonary blood flow, and the resistance to the flow has, in addition to its static value, also a time-dependent value. This dynamic component determines the increase of the distensibility. When the flow decreases, the distensibility is decreased also. It is in this way that the pulmonary blood flow is conserved.#include
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